Hydroxyurea is chemotherapy drug and is classified as an "antimetabolite." Animal and human studies have revealed evidence of side effects with hydroxyurea, pregnancy & breastfeeding. This drug can cause fetal malformations, decreased fetal viability and developmental delays. Also hydroxyurea has been reported to lower men sperm count as well. If you are a female, you should use effective birth control while taking hydroxyurea and for at least 6 months after stopping your treatment. If you are a male, you and your female partner should use effective birth control while taking hydroxyurea and for at least 6 months or at least 1 year (Droxia, Hydrea) after stopping your treatment. Read more information below.
https://medlineplus.gov/druginfo/meds/a682004.html
https://sicklecellanemianews.com/2018/02/01/hydroxyurea-treatment-men-sickle-cell-anemia-found-to-have-lower-total-sperm-count/
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